Living Image® Version 4.3.1 Software Service Pack 1 Installation and Licensing Guide Copyright 2012 Caliper Life Sciences, Inc. All rights reserved. P/N CLS135469 Rev 01 Contents Chapter 1 Before You Begin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Technical Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Chapter 2 Installing the Living Image Software On a PC . . . . . . . . . . . . . . . . . . 3 Installing the Software From the CD-ROM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Troubleshooting Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Installing the Software Over the Internet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8 Chapter 3 Installing the Living Image Software On a Macintosh . . . . . . . . . . . 10 Installing the Software From the CD-ROM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Installing the Software Over the Internet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14 Chapter 4 Activating a License . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Activating a License Over the Internet . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Manually Activating a License . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Returning a License . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21 Troubleshooting Licensing Error Messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 1 Before You Begin Requirements Technical Support on page 2 The Living Image® software can be installed from a CD-ROM or the Caliper Life Sciences web site. Table 1.1 shows where to find particular installation instructions. Table 1.1 Installation types See Page Install From Platform CD PC 3 Macintosh 10 www.caliperls.com PC 8 Macintosh 14 1.1 Requirements Hardware & Software Requirements For optimum performance, the Living Image® 4.3.1 software requires hardware and software that meet or exceed the following minimum requirements. If you will be using the 3D Multi-Modality tools, the graphics card must meet the requirements in Table 1.3. NOTE: The Living Image software only supports English operating systems. Table 1.2 Minimum hardware requirements without the 3D Multi-Modality tools Item Specification (PC or Macintosh) Processor Intel Core 2 Duo CPU or higher processor recommended RAM recommended 4 GB or greater Virtual memory 2 - 4 GB Hard drive available space Minimum: 300MB Recommended: 1 GB and above Graphics card 256MB dedicated, OpenGL2.0 or later Display 17 inch or larger Table 1.3 Graphics card requirements for the 3D Multi-Modality tools Item Specification OpenGL Version Requirement* OpenGL 2.0 and above. OpenGL Extension Requirement* GL_EXT_Texture3D Living Image® 4.3.1 Installation and Licensing Guide Chapter 1 | Before You Begin Table 1.3 Graphics card requirements for the 3D Multi-Modality tools (continued) Item Specification Graphics Card Memory Recommended: 1GB (Dedicated) Consumer Graphics Cards (Desktop/ Mobile, Windows/Mac) Supported: – NVIDIA® GeForce® 8 Series and above (8, 9, 100, 200, 300 and 400 series) – ATI Radeon™ HD 4000 Series and above (4000 and 5000 series) Recommended: – Desktop - NVIDIA GeForce GT 240 and above – Mobile - NVIDIA GeForce GT 230M and above Workstation Graphics Cards (Desktop/ Mobile, Windows/Mac) Supported: – NVIDIA® Quadro ® NVS Series and Above (NVS & FX series) – ATI FireGL ™ V5600 and Above (FireGL, FirePro & CrossFire series) Recommended: – Desktop - Quadro FX 1800 and above – Mobile - Quadro FX 880M and above *If these specifications are not met, the 3D Multi-Modality tools do not appear in the tool palette. Table 1.4 Minimum software requirements Operating System Requirement Windows Windows 7 64-bit, Windows 7 32-bit, Windows XP Macintosh Mac OS 10.5 to 10.7 1.2 Technical Support If you need technical support, please contact Caliper Life Sciences at: Telephone: 1.877.522.2447 (US) 1.508.435.9500 E-mail: [email protected] Fax: 1.508.435.3439 Address: Caliper Life Sciences US Corporate Headquarters 940 Winter Street Waltham Massachusetts 02451 USA 2 2 Installing the Living Image Software On a PC Installing the Software From the CD-ROM Installing the Software Over the Internet on page 8 2.1 Installing the Software From the CD-ROM NOTE: The Living Image® 4.3.1 software can only be installed on a Windows 7 (32-bit or 64-bit) or Windows XP operating system. Administrative privileges are required to install and configure the Living Image 4.3.1 software on Windows 7 operating systems. The Living Image software will be installed at: 32-bit application on Windows 7 32-bit OS and Windows XP– C:\Program Files\Caliper Life Sciences\Living Image 32-bit Application on Windows 7 64-bit OS – C:\Program Files (x86)\Caliper Life Sciences\Living Image 64-bit Application on Windows 7 64-bit OS – C:\Program Files\Caliper Life Sciences\Living Image The 32-bit application will work on a 32-bit or 64-bit operating system; however, the 64-bit application is recommended for a 64-bit operating system. Only the 32-bit application can be installed on a 32-bit operating system. 1. Insert the Living Image 4.3.1 software CD-ROM into the workstation computer. The Welcome screen appears. NOTE: If the Welcome screen does not appear, use Windows Explorer to navigate to \Windows\directory on the installation CD/ROM. Right-click the Install.exe file and select “Run as administrator” from the shortcut menu, then enter the local administrator’s user name and password. Figure 2.1 Welcome screen Living Image® 4.3.1 Installation and Licensing Guide Chapter 2 | Installing the Living Image Software On a PC 2. In the Welcome screen, choose a language and click OK. The Introduction screen appears (Figure 2.2). Figure 2.2 Introduction screen Indicates the application version: 64 or 32-bit 3. Review the introductory information and click Next. 4. Read the license agreement that appears. Figure 2.3 License agreement 5. To continue with the installation, accept the terms of the license agreement and click Next. The Choose Install Set screen appear. 4 Living Image® 4.3.1 Installation and Licensing Guide Chapter 2 | Installing the Living Image Software On a PC Figure 2.4 Choose Install Set screen Living Image 4.3.1 is now ready to install the standard analysis features. Data Acquisition Module - Choose this option if you are installing the software on an acquisition workstation. 3D Multi-Modality Module - Choose this option to install the 3D Multi-Modality tools. DyCE Module - Choose this option to install the DyCE tools. NOTE: The 3D Multi-Modality tools and the DyCE tools each require a separate license. 6. Click Next 7. In the Pre-Installation Summary screen, confirm that the installation information is correct, then click Install. If the Living Image 4.3.1 installer detects the Living Image 3.x application (analysis or acquisition version), you are prompted to confirm uninstallation of the earlier version (Figure 2.6). Click Yes in the confirmation message to uninstall the Living Image 3.x software and install the Living Image 4.3.1 software. Click No to terminate the installation program. 5 Living Image® 4.3.1 Installation and Licensing Guide Chapter 2 | Installing the Living Image Software On a PC Figure 2.5 Pre-installation Summary screen NOTE: If older Living Image software is installed on the acquisition computer, the Living Image 4.3.1 installer will uninstall the old software and copy all essential acquisition calibration files (CameraInfo.txt, CameraLog.txt, Background folder, LI_AutoBkgList.csv, Emfilters folder, FLReference folder, SLReference folder, CCDCal folder, if such exists) to the Living Image 4.3.1 directory. Figure 2.6 Confirmation message to uninstall older Living Image software NOTE: If the message shown in Figure 2.7 appears, click OK. The installation will proceed without any problems. Figure 2.7 Launch AnyWhere Error message 8. Click Done when the installation is finished. 6 Living Image® 4.3.1 Installation and Licensing Guide Chapter 2 | Installing the Living Image Software On a PC Figure 2.8 Install complete screen 9. After successful installation on an acquisition computer, start the Living Image 4.3.1 software and verify that you can initialize the IVIS® Imaging System. If you are unable to initialize the imaging system, contact Caliper technical support. NOTE: After you install the Living Image® software, you must activate the permanent license. If the 3D Multi-Modality and DyCE tools were installed, a separate license for each must be activated. See page 16 for more information. 2.2 Troubleshooting Installation If the error message shown in Figure 2.9 appears, it indicates that the installation cannot proceed due to limited user privileges. Click OK in the message to cancel the installation. Figure 2.9 Error message To resolve this issue, do either of the following: Login with the Administrator user account and start the installation Right-click the Install.exe file and select “Run as administrator” from the shortcut menu, then enter the local administrator’s user name and password. If installation does not proceed, please contact your IT department. 7 Living Image® 4.3.1 Installation and Licensing Guide Chapter 2 | Installing the Living Image Software On a PC 2.3 Installing the Software Over the Internet 1. Go to the download URL: http://caliperls.com/support/software-downloads.htm Figure 2.10 Caliper software download web page 2. On the web page, scroll down to Software Downloads: Optical Imaging: Living Image Software. 3. To install the software on a PC, click LI_<version>_WIN_Install.zip. The File Download dialog box appears. Figure 2.11 File download dialog box 4. Click Save. 5. When the download is complete, double-click the LI_<version>_WIN_Install.exe in the zip file. 8 Living Image® 4.3.1 Installation and Licensing Guide Chapter 2 | Installing the Living Image Software On a PC Figure 2.12 Zip file contents 6. In the Welcome screen that appears, choose a language and click OK. To continue with the installation, follow step to 3 to step 9 in Installing the Software From the CD-ROM, page 3. NOTE: After you install the software, you must activate the permanent license. See page 16 for more details. 9 3 Installing the Living Image Software On a Macintosh Installing the Software From the CD-ROM Installing the Software Over the Internet on page 14 3.1 Installing the Software From the CD-ROM NOTE: The Living Image® 4.3.1 software requires Mac OS X 10.5 or later. 1. Insert the Living Image 4.3.1 software CD-ROM into the workstation computer. The Welcome screen appears. Figure 3.1 Welcome screen 2. In the Welcome screen, choose a language and click OK. The Introduction screen appears (Figure 3.2). 3. Review the introductory information that appears and click Next. Living Image® 4.3.1 Installation and Licensing Guide Chapter 3 | Installing the Living Image Software On a Macintosh Figure 3.2 Introduction screen 4. Read the license agreement. To continue with the installation, accept the terms of the license agreement and click Next. Figure 3.3 License agreement NOTE: Only the analysis features of the Living Image® software can be installed on a Macintosh. 5. If you are installing the optional 3D Multi-Modality and/or DyCE tools, choose these options in the Choose Install Set screen. Click Next. The installation proceeds. NOTE: The 3D Multi-Modality and the DyCE tools each require a separate license. 11 Living Image® 4.3.1 Installation and Licensing Guide Chapter 3 | Installing the Living Image Software On a Macintosh Figure 3.4 Choose Install Set screen 6. In the Pre-Installation Summary screen, confirm that the installation information is correct, then click Install. The installation proceeds. Figure 3.5 Pre-installation Summary screen 7. After the installation is finished, click Done in the Install Complete screen. 12 Living Image® 4.3.1 Installation and Licensing Guide Chapter 3 | Installing the Living Image Software On a Macintosh Figure 3.6 Install Complete screen 8. Enter your user name and password in the Authenticate dialog box that appears and click OK. Figure 3.7 Authentication dialog box NOTE: After you install the Living Image® software, you must activate the permanent license. If the 3D Multi-Modality and DyCE tools were installed, a separate license for each must be activated. See page 16 for more information. 13 Living Image® 4.3.1 Installation and Licensing Guide Chapter 3 | Installing the Living Image Software On a Macintosh 3.2 Installing the Software Over the Internet 1. Go to the download URL: http://www.caliperls.com/support/software-downloads.htm. Figure 3.8 Caliper software download web page Figure 3.9 Download prompt 2. On the web page, scroll down to Software Downloads: Optical Imaging: Living Image Software. 3. To install the software on a Macintosh, click LI_<version>_MAC_Install.zip. The File Download dialog box appears. 14 Living Image® 4.3.1 Installation and Licensing Guide Chapter 3 | Installing the Living Image Software On a Macintosh Figure 3.10 File download dialog box 4. Double-click the .zip file The install icon . (In this example, the file was saved to the desktop.) appears on the desktop. Figure 3.11 Macintosh desktop 5. Double-click the install icon . The installation starts. 6. Follow step 3 to step 8 on page 10 to 13. NOTE: After you install the software, you must activate the permanent license. See page 16 for more details on activating a license. 15 4 Activating a License Activating a License Over the Internet Manually Activating a License on page 18 Activating a License Over the Internet on page 16 Troubleshooting Licensing Error Messages on page 21 The Living Image® software is licensed to individual workstations. The software provided with an IVIS® Imaging System includes a five seat license that permits you to install the software for data analysis on up to five workstations. After the software is installed, you have 30 days to activate the permanent license. The 3D Multi-Modality Tools plug-in and the DyCE plug-in each require a separate license. There are two ways to activate a license: Internet activation - Activates the license over the Internet Manual activation - For workstations not on a network NOTE: A license from Living Image 3.x cannot be transferred to Living Image 4.3.1. . 4.1 Activating a License Over the Internet 1. Start the Living Image software (double-click the icon on the desktop). The main window appears and shows the number of days that remain to activate a license for the Living Image software and the 3D Multi-Modality Tools and/or DyCE plug-in (if the3D MultiModality and/or DyCE tools were selected during installation). Figure 4.1 Activating a license over the Internet 2. Click Activate License. Living Image® 4.3.1 Installation and Licensing Guide Chapter 4 | Activating a License NOTE: To evaluate the software without activating a license, click Evaluate. 3. In the dialog box that appears, enter your user name, organization name. 4. To activate the Living Image license, enter the serial number for the software application. To activate the 3D Multi-Modality Tools license, enter the serial number for the 3D Multi-Modality tools plug-in. To activate the DyCE tools license, enter the serial number for the DyCE tools plug-in. 5. Choose the Internet Activation option and click Activate You are notified of a successful activation. Figure 4.2 Notification of successful activation of the Living Image software Specifying Proxy Settings By default, the activation connects directly to the license server on port 443. If a proxy server is used at your location, specify the proxy settings. 1. Click Proxy Settings. 2. In the dialog box that appears, put a check mark next to Proxy Settings and enter the values for the proxy server. Contact your IT department for details about the correct proxy server settings. 17 Living Image® 4.3.1 Installation and Licensing Guide Chapter 4 | Activating a License Figure 4.3 Select proxy settings 4.2 Manually Activating a License For manual activation, generate a machine ID file and e-mail it to Caliper technical support. You will receive a license file by e-mail that can be manually activated. 1. Start the Living Image software (double-click the icon on the desktop). The main window appears and shows the number of days that remain to activate the license. 2. Click Activate License. 3. In the dialog box that appears, enter your user name, organization name, and software serial number. 4. Choose the Manual Activation option and click Activate. 5. In the dialog box that appears: a. Click Save to file. a. Select a directory for the file and click Save. 6. E-mail the machine ID file to [email protected]. 18 Living Image® 4.3.1 Installation and Licensing Guide Chapter 4 | Activating a License Figure 4.4 Manual license activation 7. After you receive the license file from Caliper technical support, click the Browse button navigate to the license file. Figure 4.5 Browse to the license file 8. Click Close. The license is activated. and 19 Living Image® 4.3.1 Installation and Licensing Guide Chapter 4 | Activating a License Editing a License File Sometimes it may be necessary to edit a license file for renewal or repair purposes. To edit a license file: 1. Open the license information dialog box (select Help → License Information on the menu bar). 2. Right-click the serial number of the file license and select Edit File-Based Licenses from the shortcut menu. Figure 4.6 License Information 3. In the dialog box that appears, use the Add or Delete buttons configuration. Figure 4.7 Edit the license configuration 4. Click Save. 5. Restart the Living Image software. to edit the license 20 Living Image® 4.3.1 Installation and Licensing Guide Chapter 4 | Activating a License 4.3 Returning a License You can return a license so that it is available for use on another workstation. If you have renewed a license, you must return the old license before you can activate the new license. To return a license: 1. Select Help → License Information on the menu bar. 2. In the dialog box that appears, click Return License and click Close. Figure 4.8 Return a license 4.4 Troubleshooting Licensing Error Messages Table 4.1 Licensing error messages Error Message Possible Causes Solutions Unable to send application activation to remote server. The workstation is unable to reach the Caliper Licensing server on the Internet on port 443. This may be because the workstation is not connected to a network or the network firewall is preventing communication on port 443. 1. Verify that the workstation can connect to the Internet. 2. Check the local firewall policies of the IT group responsible for the network. The activation of the fulfillment is denied by the activation policy because max extra acts exceeded #9679-7028. The maximum number of seats available on the license have been activated. 1. Return a Living Image 4.3.1 license from another workstation. 2. Acquire additional license sets from Caliper Life Sciences. 21