A Portable Bioimpedance Spectroscopy Measurement System for Congestive Heart Failure (CHF) Management

M.K. Delano and
Tom 0’Dwyer
A PORTABLE BIOIMPEDANCE
SPECTROSCOPY MEASUREMENT
SYSTEM FOR CONGESTIVE HEART
FAILURE (CHF) MANAGEMENT
An estimated five million people are currently diagnosed with congestive heart failure (CHF) in the United
States, with over 400,000 new diagnoses annually. Almost one in two patients will be readmitted to the hospital
within four to six months of discharge. Up to 50% of these early readmissions may be prevented if symptoms
are recognized early enough. Bioimpedance measurements have been shown to be predictive of heart failure
decompensation up to 14 days before an event occurs. We have developed a portable bioimpedance system
that can measure body impedance from 1 kHz to 1 MHz. The system uses the magnitude ratio and phase
difference detection method to calculate the magnitude and phase of the measured impedance (see Figure 1).
The system is enclosed in an aluminum box (see Figure 2) and can be used with four coaxial cables to reduce the
impact of stray capacitances. The device has been characterized with RC networks and is being tested with
healthy volunteers.
ISine
ZBody
IA1
VBody
VBody
Gain Phase
Detector
R1
IA2
VRef
VRef
Figure 1: A schematic overview of the magnitude ratio and phase
difference detection method. A fixed sinusoidal current is driven
through the body and a sense resistance. The voltage is amplified
and measured by a gain phase detector chip (AD8302).
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Figure 2: The portable bioimpedance spectroscopy
measurement system inside the enclosure.
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